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Glossary of Antiarrhythmic Drugs

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Class I Na+ Channel Blockers?
(1A)
Disopyramide (Norpace)
Procainamide (Procan)
Quinidine (Quinidex)
Class I Na+ Channel Blockers (1b)?
Lidocaine (Elamax/Lidoderm)
Mexiletine (Mexitil)
Tocainide (Tonocard)
Class I Na+ Channel Blockers (1c)?
Flecainide (Tambocor)
Propafenone (Rhythmol)

Others:
Adenosine
Digoxin
Class II B-Blockers
Esmolol (Brevibloc)
Metoprolol (Lopressor,Toprol)
Pindolol (Visken)
Propranolol (Inderal)
Class III K+ Channel Blockers
Amiodarone (Cordarone)
Bretylium (Bretylol)
Sotalol (Betapace)
Class IV Ca++ Channel Blockers
Diltiazem (Cardizem, Tiazac)
Verapamil (Calan, Covera, Isoptin)
Mechanism of action of Class IA antiarrhytmics?
Na+ Channel Blockers
class 1A slows phase 0 depolarization
Mechanism of action of Class IB antiarrhytmics?
Na+ Channel Blockers
Class 1B shortens phase 3 repolarization
Mechanism of action of Class IC antiarrhytmics?
Na+ Channel Blockers
Class 1C markedly slows phase 0 depolarization
Mechanism of action of Class 2 antiarrhytmics?
Class II B-Blockers (supresses phase 4 depolarization)
Mechanism of action of Class 3 antiarrhytmics?
Class III K+ Channel Blockers (prolongs phase 3 repolarizaion)
Mechanism of action of Class 4 antiarrhythmics?
Class IV Ca++ Channel Blockers (shortens action potential)

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