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Glossary of ANS Drugs

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á1 Location
located on smooth muscle cells.Heart
produce muscle contraction
á2 receptors act on ...
the brain as a negative feedback causing less norepinephrine to be released.
â1 receptors act on...
the heart. Smooth muscle They cause the formation of cAMP, a second messenger. They increase heart rate and contractility.
â2 receptors are in
in the bronchi. They cause dilation.
Muscarinic receptors...
Excite or inhibit and increase Ca++ into the cell to initiate contraction of smooth muscle.
They increase secretion of exocrine glands.
Alpha and beta adrenergic agonist.
Epinephrine
Norepinephrine receptor action
Alpha 2 adrenergic agonist
Albuterol acts on...
Beta2 agonist
Clonidine
Classification: Adrenergic alpha 2 agonist
Use: Centrally acting to decrease blood pressure. Used in alcohol withdrawal to reduce blood pressure response.

Decreases release of norepinephrine in the brain and decreases the effect of the sympathetic nervous system.
Beta 1 receptors act on...
cardiac. Stimulation increases heart rate and contractility
Beta 2 receptors are
in the bronchi. They cause dilation
Procainamide
Used To maintain NSR after conversion. Ventricular ectopic beats and Ventricular tachycardia
Quinidine
maintain NSR after conversion. Ventricular ectopic beats
Ventricular tachycardia
Lidocaine
Use: Ventricular arrhythmias
Propranolol (Inderal)
Management of angina,
arrhythmias,
supraventricular tachycardia,
atrial fibrillation/flutter and
PSVT.
Esmolol
Management of supraventricular tachycardia,
atrial fibrillation/flutter
Amiodarone
IV use for Ventricular fibrillation/tachycardia.

PO use for recurrent ventricular tachycardia and to maintain NSR with atrial fibrillation/flutter.
Diltiazem (Cardizem)use:
Use: IV for PSVT
Verapamil
PO for chronic suppression of PSVT and atrial fibrillation/flutter.
Adenosine (Adenocard)
Use: Restore NSR after PSVT .
MOA: Reduces conduction of AV node.
Antiarrhythmics
Procainamide
Quinidine
Lidocaine
Propranolol (Inderal)
Esmolol
Amiodarone
Diltiazem (Cardizem)
Verapamil
Adenosine (Adenocard)
Antianginals
Isosorbide dinitrate (Isordil)
Diltiazem

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