Glossary of ANS Drugs
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- á1 Location
- located on smooth muscle cells.Heart
produce muscle contraction
- á2 receptors act on ...
- the brain as a negative feedback causing less norepinephrine to be released.
- â1 receptors act on...
- the heart. Smooth muscle They cause the formation of cAMP, a second messenger. They increase heart rate and contractility.
- â2 receptors are in
- in the bronchi. They cause dilation.
- Muscarinic receptors...
- Excite or inhibit and increase Ca++ into the cell to initiate contraction of smooth muscle.
They increase secretion of exocrine glands.
- Alpha and beta adrenergic agonist.
- Norepinephrine receptor action
- Alpha 2 adrenergic agonist
- Albuterol acts on...
- Beta2 agonist
- Classification: Adrenergic alpha 2 agonist
Use: Centrally acting to decrease blood pressure. Used in alcohol withdrawal to reduce blood pressure response.
Decreases release of norepinephrine in the brain and decreases the effect of the sympathetic nervous system.
- Beta 1 receptors act on...
- cardiac. Stimulation increases heart rate and contractility
- Beta 2 receptors are
- in the bronchi. They cause dilation
- Used To maintain NSR after conversion. Ventricular ectopic beats and Ventricular tachycardia
- maintain NSR after conversion. Ventricular ectopic beats
- Use: Ventricular arrhythmias
- Propranolol (Inderal)
- Management of angina,
atrial fibrillation/flutter and
- Management of supraventricular tachycardia,
- IV use for Ventricular fibrillation/tachycardia.
PO use for recurrent ventricular tachycardia and to maintain NSR with atrial fibrillation/flutter.
- Diltiazem (Cardizem)use:
- Use: IV for PSVT
- PO for chronic suppression of PSVT and atrial fibrillation/flutter.
- Adenosine (Adenocard)
- Use: Restore NSR after PSVT .
MOA: Reduces conduction of AV node.
- Isosorbide dinitrate (Isordil)
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