Glossary of 8. Viral Hepatitis

Start Studying! Add Cards ↓

What's the incubation period of:
-Hep A
-Hep E
-Hep D
-Hep B
-Hep C
A = 2-6 wks
E = 3-6 wks
D = 3-13 wks
B = 8-24 wks
C = 2-52 wks
Which hepatitis have onset thats
Acute = A, E, D.
Insidious = B, C.
How are Hepatitis A and E transmitted?
How are Hepatitis B, C, and D transmitted?
Which hepatitis types exhibit chronic states?
B, C, and D.
How would you diagnose Hepatitis due to alcoholic cirrhosis?
AST high
ALT low
For which hepatitis viruses do immunizations exhist?
-Hep A
-Hep B
What food is Hep A esp. associated with?
What 2 antibodies are used as serologic markers of HAV?
1. Total Anti-HAV
2. IgM anti-HAV
what does Total Anti-HAV indicate?
Immune status; it's a life-longer marker.
-Does NOT distinguish acute from past infection
What does IgM Anti-HAV indicate?
Acute disease.Remains 6 months.
What are the normal serologic markers on an Acute Viral Hepatitis panel?
1. IgM Anti-HAV
2. HBsAg
3. IgM Anti-HBc
4. Anti-HCV
What's another name for Hep B?
Serum hepatitis
What is the danger of dying from hepatitis B in babies that recieve it perinatally?
Low; but 95% chance of being a carrier.
What shot is given to babies in case of Hep B transmisison?
what is H-BIG?
Anti-hepatitis B immunoglobulin; a passive antibody for immediate resistance to the organism.
Who is at increased risk of developing chronic hep B?
children under the age of 5.
What is the 1st marker in Hep B?
When does it disappear?
What does it infer?
-Gone with symptoms clearing
-Infers infectivity
Which marker indicates ACUTE Hep B infeciton?
Anti-HepB core IgM
when does IgM Anti-HBc rise and fall?
-Rises soon after HBsAg; falls soon after HbSAg, but TOTAL stays high.
Which Hep B marker infers recovery and immunity?
-When does it appear?
Anti-HBs; rises during convalescence.
When does anti-HBe begin to replace HBe-Ag?
When symptoms begin to disappear
What can evaluating HBeAg and Anti-HBe levels do for evaluation of hepatitis B?
Signal chronic infection; the antigen will remain for months to years, instead of only weeks.
What 2 markers indicate chronic Hep B infections?
-HBeAg present way too long
-HBsAg remains elevated instead of disappearing with symptoms.
what are 2 types of chronic HB?
What is the difference btwn them
Chronic active
-Chronic persistant

-Active does not seroconvert HBeAg to antibody.
-Persistant does.
What are the 2 types of Hep D infection?
-Co-infection with Hep B
What is the deal with Hep D superinfection?
-Occurs AFTER Hep B infection.
-Usually becomes chronic
-Hi risk severe chronic liver disease.
What markers can we detect for Hep D in the lab?
Anti-HDV Total
what marker is useful in detecting hepatitis C?
how do we differentiate chronic infections from acute?
Acute - normal ALT peak/decline
Chronic - crazy ALT levels
What is significant to remeber re: Anti-HCV?
it is not protective.
What 3 methods are used for supplemental testing for HC after the serological screen?
-Recombinant immunoblot assay
-Reverse Transcription PCR

Add Cards

You must Login or Register to add cards