Glossary of 14 - Pathology: Myobacteria
Other Decks By This User
- Do Mycobacteria produce toxins?
- 2 ways in which Mycobacteria damage the host
Hypersensitivity response (DTH = Type 4)
- Agent that causes TB
- Mycobacterium tuberculosis Homonis (Koch's Bacillus)
- Other name for Mycobacterium Leprae
- Hansen's Bacillus
- Trasmission route of TB
- DROPLET (larger than aerosols)
- Mycobacterium TB is resistant to ________
*surfaces must be disinfected to prevent spread
- Total cases of TB worldwide
- 88 M
- Portion of the world infected with TB
- # of TB deaths annually
- 1-3 M
*highest mortality for any infectious disease
- When did TB rates in US climb?
- 1985 with the rise of MDR strains and AIDS
- Doubling time for TB
- 24 hours
- How long are cultures kept before being declared negative?
- 6 weeks
*6 months with solid media
- Modern laboratories should be using ______ media to decrease incubation times
- Modern laboratories should be capable of doing a sputum smear for ______ within 4 hours
- Acid-fast bacteria
- Solid media for TB
- Lowenstein-Jenson media
- Immunofluorescent stain for TB
- Colony morphology of TB
Bread crumb look
- TB liquid growth media
- Virulence factor that causes TB to stick together
- Primary TB characteristics
- Self-limited in 95% of cases
- What is a Ghon Complex
- Granuloma in the upper Lung and Mediastinal (hilar) Lymph Node
- Progressive Primary TB only occcurs in these 2 groups of people
- IC'ed Adults
Children -> TB meningitis
- Secondary Miliary spread via a Pulmonary Vein results in...
- organisms return to the left ventricle and pumped throughout the body
- Secondary Miliary spread via Pulmonary ARTERY results in...
spread within the lung
- What to look for when reading PPD skin test
- Vaccine used for TB
- BCG vaccine = live attenuated
- Why is BCG not used in US?
- because TB clinical symptoms is rare in US and we want to be able to test for exposure
- BCG's only clinical use in the US
- used for treating Bladder Cancer
- What does TB do to the brain?
- TB Meningitis can obstruct the flow of CSF leading the Hydrocephalus
- Site of brain most often affected by TB
- Base where CN are located
- 2 ways of getting GI tuberculosis
- 1. swallowing expectorated TB from lungs
2. M. bovis ingested via contaminated milk
- Most common agent of Mycobacterial Entercolitis
- M. Avium Intracellulare
- GI MAI almost occurs exclusively in these people
- Late stage HIV
- 1st bacterium ever discovered
- M. leprae
- 2 clinical forms of Leprosy
- 1. Lepromatous (worse)
- M. leprae prefers these areas of body
- cooler areas of skin, such as face and extremities
- Transmission of M. leprae
- PROLONGED, close contact
- Animal M. leprae is found in
- M. leprae cannot be cultivated on...
Can be cultivated on...
- artificial media
- Accurate diagnosis of leprosy relies on....
- skin biopsy that is compatible with the clinical picture
- Mycobacterium Avium Intracellulare primarily causes a disseminated disease in ________
- IC'ed hosts
- MAI can cause this disease in normal hosts
- Chronic lung disease
- CD4 count when MAI usually infects
- MAI colony morphology
- 2 cases where M. kansasii may present
- 1. old person with pre-existing lung disease
2. young person with HIV
What mircobe is this?
- Mycobacterium Avium Intracellulare
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