10. Lymphoma
Terms
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What are lymphomas?
Who diagnosis them? -
SOLID TUMORS
-Diagnosed by pathologists. - What is the formal definition of lymphoma?
- A heterogenous group of malignant disorders originating from immune cells; invade the BM secondarily.
- What are the 2 classifications of lymphoma?
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1. Hodgkin's lymphoma
2. Non-hodgkin's lymphoma (NHL) - What patients get Hodgkin's?
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2 groups!
-from 15-35 yrs olds
-over 50s. - What symptoms must be present in order to diagnose Hodgkin's?
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1. Nodal changes - in cells AND stroma - architecture in general
2. Clinical symptoms. - What is the major clinical symptom of hodgkin's?
- Enlarged, non-painful, rubbery cervical lymph nodes.
- What type of cell is seen in hodgkin's?
- REED-STERNBERG CELLS - huge cells that really jump out.
- Are Reed-sternberg cells alone enough to diagnose Hodgkin's?
- No - can show up in viral infections like mono, too.
- What is the med tech's role in diagnosing Hodgkin's?
- Recognizing Reed-Sternberg cells on the bone marrow aspirate; distinguish it from Megakaryos, Osteoclasts, and Histiocytes.
- What is the prognosis of younger patients with Hodgkin's?
- Excellent - w/ chemo and radiation often go into remission.