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Glossary of ref guide

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0.22 micrometer
Min pore size required for membrane filtration for sterilization
1 quart
960 ml
10 angstrom
1 nanometer
100 clean room
Not more than 100 particles per cubic ft of 0.5 mcm or larger size
10-20 mcg/ml
Normal bld serum conc DILANTIN
10-20%
% of alcohol found in wine
120 days
Life span of RBC
120mg
Min weighable quantity for class A rx balance
12-14 seconds
Normal range of prothrombin time
1-5 seconds
Normal activated partial thromboplastin time
15%
Acceptable ratio for 10 yr old rx net profit to net worth
180mg/dl
Normal threshold for glucose in the kidney
1st line antihypertensive agents
HCTZ, atenolol
1st pass effect of metabolism
Rapid degradation of a drug by liver enzymes
1st trimester
Risk teratogenesis is highest
2 variances
F distribution compares
2,4,6 trinitrophenol
High conc of H3O ions when dissolved in water
200 units of insulin per day
Insulin resistant
240mg/dl
High cholesterol
253 nm
Sterilization by UV radiation – wavelength
2ndary response
Humoral immunity, antigen recognized by memory cells enters the blood
2ndary structure of protein
Alfa-helix, beta sheet, beta bend
3.5 to 5meq/L
Normal adult plasma conc of K
30% of over the labeled potency
Max % of overages –limited
320 nm UV light
Sunscreen products should cover
5 days
Ketorolac trmt restricted trmt
5 fluorouracil
Fluoronation will result into a well known cancer drug
5 to 7%
Acceptable ratio for net profit to net sales
50 units of insulin per day
Normal pancreas secretion
65% w/w
Sucrose conc retard growth of microorganisms
72 hours
Partial filling of sched 2
8 to 10%
Alcohol content of low iso-alcohol elixir
80%
Ribosomal rna
80-120 ml/min
Normal renal creatinine clearance
9 TIMES
Conc reactant alfa is triple in the rxn that is in 2nd order, rate of rxn would increase
a. fungi
Cancidas treat infections
AAC –antibiotic associated colitis
Clindamycin-adv effect
Absolute density
Ratio of mass of an object measured in a vacuum at specific temp to vol (ml) of an object at the same temp
Abx trmt UTI
Cipro, cotrimoxazole, nitrofurantoin
Acarbose
Precose
Accelerated stability testing of pharmaceuticals
Temperature, humidity, light
Accidental overdose drug poisoning
Charcoal plus, actidose with sorbitol, actidose aqua
Accolate
LTRA
Acct receivable collection
Year end account receivable
Ac-ti-sol
Disintegrant in manufacturing tablets
Acetanilide
CH3CONHC6H5
Acetazolamide
Inhibition of carbonic anhydrase enzyme
Acetone
Semipolar solvent
Acetylcysteine
Mucolytic or reduce viscosity of mucous
Achlorhydria
Stoppage or impaired secretion of HCl in the stomach
Acid fast stain
Mycobacterium species of bacteria
Acid test
Measures rx liquidity
Acid test ratio
-liquidity of rx, ratio of quick asset to current liability, the closer the current liability to a rx quick asset the more ideal the acid-test ratio
Action of histamine
Gastric acid stimulation, vasodilation, contraction of smooth muscle
Actiq
Fentanyl
Active immunization
Mumps, rabies, plague
Active metabolite of primidone-prodrug
Phenobarbital,PEMA
Actuary
Person who works for ins co
Advair discus
Fluticasone and salmeterol, bid dosing used for prevention of acute attacks of asthma
Adverse eff – Insulin therapy
Hypoglycemia, lipoatrophy, lipohypertrophy
Adverse effects of aminoglycosides
Ototoxicity, nephrotoxicity, curaremimetic eff
Aggrenox
Aspirin, dipyridamole
Agranulocytosis
Adv effect of clozaril
Airborne disease
Measles
Albumin
Major plasma protein involved in drug binding
Alcohol as disinfectant
70% conc alcohol ionizes the best and provides optimum disinfection, wets the skin smoothly and evaporates slowly
Alfa-methyl noradrenaline
Acts as false neurotransmitter
Allegation method
75 25(75% alc)
Allegra
Histamine H1 rec antagonist
Allergic to mesalamine
Avoid asacol , pentasa,
Alpha 1 receptors
Doxazosin,terazosin, prazosin
Alpha 2 rec
Prevents the release of noradrenaline
Alpha error
5% - significant
Alprazolam
Bz –geriatric pt
Amaryl
Htn
Ames test
To find out if the subs is carcinogenic
Amifostine
Cisplatin toxicity
Amiloride
Diuretic, acts inhibit Na,K, Atpase
Aminogluthethimide
Cushing syndrome
Amlodipine
CCB
Ammonium Cl , ammonium nitrate, cacl
Reduce absorption of acidic drugs
Amrinone
Inodilator
Amyl nitrite
Cyanide poisoining
Anafranil
OCD
Analysis of variance
Check for significance between 2 or more grps of means
Angiotensin II
Vasoconstriction
Angiotensin II antagonist
Diovan, cozaar, avapro
Aniline
Lowest pkb value
Antabuse
Avoid taking: synophylate elixir and elixophyline elixir
Antagonizes action of Opiod drugs
Naloxone, natrexon, nalmefene
Anterior pituitary – hormone
Growth hormones, thyrotropic
Antihemophilic factor- factor 8
Pt w/ hemophilia
Antihistamines with NO sedation prop
Astemizole, cetirizine, terfenadine
Antimicrobial agents
Isopropyl alcohol, phenol, hydrogen peroxide
Antioxidant
Addition of ascorbyl palmitate in manufacturing process
Antitoxin, hyperimmune sera, immuneserum globulin
Intro of ready made antibodies into a normal person in order to induce immunization against a particular disease
Antitussive property
Codeine, dextromethophan, benzonatate
Anuria
Absence of secretion of urine by the kidney
Anzemet
BPH ;Monitor with cat scan
Aplastic anemia
Drug induced hematological disorder assoc w/ highest morbidity and mortality rates
APTT
Test to monitor heparin therapy
Arava
Leflunomide antirheumatic
Arimidex
Breast cancer
Arlex
Do not use for more than 10 days- allergic conjunctivitis
Arm ratio test, rider graduated beam test, shift test
Required to check sensitivity of class A weighing prescription balance
Arthralgia
Principal adverse effect of Pyrazinamide
AST
Regularly check- Precose
Asthma attack elevated levels
TLC,FRV,RV
Asthma attack- factor trigger
Tobacco smoke, exercise, cold air
Atacand
Angiotensin II receptor antagonists
Ativan
Sed hyp antiemetic for cancer chemo n/v
Attenuation
Process of weakening the disease producing capacity of pathogens
AUC
Amt of drug systematically absorbed
Avalide
Irbesartan and HCTZ
Avita cream
Once a day
Avoid sunlight
Hydrodiuril, mellaril, sumycin
Avoid with depression
Clonidine, methyldopa, reserpine
Azopt
Glaucoma
B and T lymphocytes
Immune responses of the body
Bacteremia
Presence of bacteria without multiplication in blood
Barium sulfate
Used for roentgenography for exam of stomach and colon; causes constipation,mix w/ food
Basic drugs
Beta globulin, acid glycoprotein
Baycol
HMG COA
Benzyl alcohol
Preservative
Beta carotene
Helps in visual adaptation in darkness
Beta error
hypothetical value of a parameter is the same as the observed value of a parameter
Beta islets of langerhans
Sulfonylurea stimulates the release of insulin in the pancreas
Beta max
0.576 x c
Betapace
Pretrmt – check creatinine clearance
Betapace AF
Dosing admin, PPI
Bias
systematic difference from the true value
Bile acid binding resins
Questran, colestid, welchol
Bile salt
Emulsifying agent for metabolism of lipid in the duodenum
Binomial distribution
P + Q = 1
Binomial experiment
Each trial results in an outcome that is classified as success or failure, experiment consists of n-repeated trials, probability of success remain constant from trial to trial
Blending
Increase in mutual solubility of 2 partially miscible liq by the addition of a 3rd subs
Bleomycin
Acts on replication levels of protein synthesis pulmonary fibrosis
Body mass index
Weight (kg) / height (meter) 2
Bradykinin
Causing dry cough receiving ACE
Brethine
Severe headaches
Bromocriptine
Antiparkinson- dopamine rec agonist
Bromocriptine- prolong use
Monitor thru pulmonary fxn
Brownian motion
Random motion of solute particles in colloidal dispersion
Brownian motion of colloidal particles reduced by
Increasing viscosity of dispersion medium
Bulk laxatives
Metamucil, Citrucel, mitrolan
Bumex
Loop diuretic
Bupropion
Smoking cessation
Butorphanol
Opiod nasal spray
C = C
Requires the greatest amount of energy
C/I in trmt of BPH
Benadryl, entex, atrohist plus
Cabbage and cauliflower
Good source of vit k
Calcarb
Highest amount of elementary calcium
Calcitriol
Mobilizes bone calcium into blood
Calcium gluconate
Lowest amt of elementary calcium
Calcium phosphate
Diluent avoid with TCN
Callhydryl lotion, bactrim susp, pen g procaine depot inj
Carafate
Constipation
Carboplatin
Major side eff; nausea and vomitting
Carrots
Vit a source
CAT
Synthesis of acetylcholine occurs in nerve fibers in the presence of
Catabolic reaction
Breakdown of complex molecules such as protein, lipid and polysaccharide into simple molecules such as carbon dioxide, water and ammonia
Catapres TTS
Replace every week
Category x
Restricted during pregnancy
Cationic agents
Class of surfactants widely used as preservative
Causes hemolytic anemia with G6PD def
Oxidant drug, ingestion of fava beans, certain types of infection
Ceftriaxone
Meningitis
Certified colors
FD and C, D and C, External D and C
Chemo induced nausea and vomiting
Zofran, kytril, anzemet
CHF patients
Carefully prescribe doxorubicin, esmolol, daunorobicin
Chi Square test
2x2 =1
Chloride ions
Assoc with gaba rec to produce tranquilizing effects
Chlormerodrin(radioisotope)
Pharmaceutical use- localize brain tumors
Chlorpropamide
Avoid in old pt – sulfonylurea
Cholelithiasis
Obstruction of gall bladder by cholesterol stone
Cholestatic Jaundice
Chlorpromazine,Erythromycin estolate
Cholesterol
Major precursor of steroid hormone
Cholinergic drugs use
Glaucoma, atony of bladder, myasthenia gravis
Chromophores
Part of the molecule that absorbs the ultraviolet light or visible light
Cimetidine
H2 rec antagonist
Ciprofloxacin
Antibacterial, inhibit bacterial DNA synthesis by blocking DNA gyrase
Circle
X2 + y2 =1
Cis
Same side
Cisplatin
Ototoxicity, renal toxicity, n/v
Cl tetani
Anaerobic organism
Class 1
Recall class – potential heath hazard
Class 1 C antiarry
Restricted only for life threatening arrh
Climara transdermal
Change every week
Clofazimine
Longest half life
Clomid
Ovulatory dysfunction
Clorpres
Diuretic, chlorthalidone
Closed-ended question
Requires an answer in the form of yes or no
CMC
Minimum conc w/c physical properties of solns of assoc colloids (electrical conductance & osmotic pressure show marked changes
CNS stimulation
Adv effect assoc w/ quinolone drp abx
Cold cream
w/o emulsion
Cold sterilization
Removing 0.2 mcm or larger particles incl microorganisms from the solution
Collected blood storage temp
4 to 6 degrees
Combivent
Ipratropium and albuterol sulfate
Compliance
Overutilization /underutilization of drug, admin of meds at inappropriate times
Compound W
Salicyclic acid
Conc of drug at rec site
Does not affect protein binding of drug
Conjugation
Transfer of genetic info from 1 cell to another cell is carried out by the plasmid
Copayment
Pt pay specified amt of the cost of rx and 3rd party to pay remaining cost
Corn starch
Increase flow property of granules
Cortisol
Naturally occurring glucocorticoid
Cotazym, pancrease, zymase
Useful dietary supplement prdts of pancrelipase enzymes
Cozaar
Blocking ace type II
Current assets
Cash, A/R, inventory
Current liability
Notes payable beyond 1 year
Cyclert (pemoline)
Cns stimulant
Cyclobenzaprine
Centrally acting muscle relaxant
Cyclosphosphamide
H cystitis
Cyclosporine allergy
Avoid sandimune and gengraf
Cytoxan
H cystitis or bladder toxicity
D list
Drugs withdrawn
Dalmane
BZ with prolonged duration of action
Dantrolene
Doc for MS
Dapsone
Abx inhibit the synthesis of folic acid from PABA
Dark field
Unstained living or difficult to stain organism
Darvocet overdose
Respiratory depression with cheyne storke
DDAVP
Synthetic analogue of pituitary hormone
Defective teeth and bones
Principal side eff of TCN
Deferoxamine mesylate
IM, IV,SC
Degree of freedom in t distribution
N – 1
Demeclocycline
Trmt inappropriate secretion of ADH
Denaturation of protein occur
Heat, strong acid, organic solvent
Density
Weight
Depakote
Acts by increasing the conc of GABA
Desmopressin
Used for diabetes insipidus, hemophilia a, williebrand’s dz
Dextran
Polysaccharide
Diabenese
When taken with benadryl causes flushing , throbbing headache, difficulty in breathing, n/v, weakness, blurred vision
Diabetes – long term complication
Cataract, renal failure, peripheral neuropathy
Diabetic ketoacidosis
Rapid pulse, presence of glucose and acetone in urine, acetone breath
Diarrhea
Structure activity relationships would eliminate side effects of Ampicillin
Diffusion
Transfer of drug from high conc to low conc
Digoxin
Avoid taking Erythromycin, Quinidine, Colestipol
Dihydrostreptomycin
Metabolite prdts of streptomycin , cause deafness
Dilantin adverse effects
Gingival hyperplasia, SLE, ataxia
Dilatant flow
Shear thickening system
Diphtheria
Prepared from a toxin
Diphydotestosterone
Prostate cancer
Diphydrotachysterol
Trmt of tetany, idiopathic tetany, hypoparathyroidism

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