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Glossary of Ren drugs

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Created by dmangrola

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Renin Inhibitor
Eg. Aliskiren- generic name
Tekturna-trade name
aldosterone inhibitor
eg. Spironolactone, eplerenone
hyperkalemia
Carbonic anhydrase inhibitor
eg.Acetazolamide, Methazolamide
hypokalemia, CNS effects
osmotic diuretics
cannot create a maximally concentrated or diluted urine.
eg. mannitol
Loop diuretics
eg. Lasix, furosemide, sulfa drug, bumetanide, ethacrynic acid, torsemide
Thiazide diuretics
eg. chlorothiazide, chlorothalidone, hydrocholothiazide, indapamide, metolazone.
used to prevent kidney stones, and treat nephrogenic diabetes insipidus, HTN
Collecting Duct Diuretics
(K sparing diuretics)
block sodium channel on principle cells.
eg. amiloride, triamtere, spironolactone, eplerenone
hyperkalemica

Vasopressin agonists
e.g. desmopressin and vasopressin

used for patients with septic shock, ventricular fibrillation, it activates both V1a and V2 receptors

vasopressin antagonist
e.g. conivaptan and tolvaptan
used to treat hypervolumic hyponatremia (CHF and cirrhosis)and euvolumic hyponatremia due to SIADH

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