Glossary of Diuretics, Anti-HTN, HF, Vasopressin, Desmopressin
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- What are the drugs of choice for someone with migraines and HTN?
- Beta blockers
- What are the drugs of choice for someone with previous MI and HTN?
- Beta blockers or
- What are the drugs of choice for someone with heart failure and HTN?
- ACEI or Beta blockers
- What are the drugs of choice for someone with no structural heart disease and at risk for HF?
- Would you use Metroprolol with HF?
- Why would you use Metroprolol for HF?
- Start out at low dose and slowly increase it to prevent remodeling. It is a negative inotrope but paradoxically helps with HF
- If a patient is in the ER with pulmonary edema and HF what would you do?
- Give loop to decrease preload and decrease fluid in lungs.
- What is the MOA in HF?
- Dilate veins to decrease preload.
- If you use a loop diuretic to treat HF, what effect would it have on CO? Why?
- None really. On a healthy heart it will decrease CO, but d/t Frank Starling curve in HF it is flat.
- A stabilized patient with HF is going on home on what drugs?
- Beta blockers
Diuretic to prevent future edema
- Why is eplerenone used with HF?
- it is an aldosterone blocker --> prevents remodeling d/t too much aldosterone
- What is the biggest SE of eplerenone?
- What is the biggest problem with hyperkalemia?
- A patient is in the hospital with HF on loops and NTG but they didnt help enough, what can you give them?
- Postitive inotropic drug--dont use DIGOXIN
- What can you use in a patietn with stage D HF?
- A patient with HF taking beta blockers and a loop, but they have a history of angioedema, what do you use?
- When would you use hydrazaline and isosorbide dinitrate in HF patients?
- When they cant tolerate ACEI or ARBs due to pregnancy or bilateral renal artery stenosis (RAS)
- What are the drugs of choice for someone with HTN and asthma?
- Why use beta blockers with HTN and MI?
- decrease mortality
- What is high blood pressure?
- What is the goal of BP in a diabetic?
- Below 130/80
- What is the biggest SE of nifedipine?
- Reflex tachycardia
- What is the best diuretic to treat liver disease and ascites?
- aldosterone antagonist (spironolactone)
- What are the drugs of choice for someone with HTN and pregnant?
- Is clonidine an agonist or antagonist?
- alpha 2 agonist
- Which drugs can you use to treat hypercalcemia?
- Would you use vasopressin for nephrogenic diabetes insipidous?
- No, you use thiazides and fluid.
- What would you use for central diabetes insipidous?
- Desmopressin because it is more V2 selective.
- If a child is taking desmopressin for bedwetting and wakes up with a seizure--what is going on?
- Drank too much at bedtime --> hyponatremia --> seizure
- If a person has gout, HTN, bilateral RAS, and a HR of 50 bpm, what do you give them?
- DHP Ca channel blocker
- What effect does ACEI have on CO and HR in treatment of HTN?
- What can cause you to switch from an ACEI to an ARB?
- cough and angioedema
- Would you use an ACEI with HTN and COPD?
- Yes, but not 1st choice
- If a patient has a crushing injury and a problem with the kidneys and you need to alkaline the urine, how would you do this?
- Carbonic anhydrase inhibitors (CAI)
- How do you get loss of K with loop diuretics?
- in the collecting duct --> Na for K
- If you have increased TG, normal LDL, and low HDL--what would you use?
- Niacin or fibric acid derivative
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