BISCI exam #1
Terms
undefined, object
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- takes up space and has mass
- matter
- what are the 3 forms of matter?
- solid, liquid, gas
- substance that can't be broken down to different properties
- element
- everything is composed of_____
- elements
- what do properties include?
- density , solubility , (physical or chemical)
- how many natural elements are there?
- 92
- what are the building bloacks of all matter?
- elements
- what elements make up protein, fats, and nucleic acids?
- carbon, nitrogen, hydrogen, oxygen
- what elements make up 95% of our bodies?
-
1.carbon
2.hydrogen
3.nitrogen
4.oxygen
5.phosphorus + sulphur - what element makes up 60% of our body?
- oxygen
- the smallest part of an element that displays properties of that element
- atom
- what is the atomic #?
- # of protons
- What is the atomic mass?
- # of protons + neutrons
- Where is the atomic# located on the periodic table?
- lower right hand corner of the element box
- Where is the atomic mass located on the periodic table?
- upper left hand corner of the element box
- #of portons = #of _____
- electrons
- most of mass = ________
- empty space
- this states that most of the time electrons are where they are supposed to be(except when we look thru microscope-it can trick us)
- Bohr Model
-
atomic mass
-atomic# = ? - # of neutrons
- constant, resistant to movement
- mass
- changes based on gravity
- weight
- how is periodic table arranged?
-
"groups"-verticle columns
"periods"-horizontal rows - What does the "groups" show?
- -# of electrons in the outer most shell
- which group has a full outer shell?
- group 8 (all the way to the right)
- what sign do you put when the element gains an electron?
- - (negative sign)
- have the same # of protons, but different # of neutrons - has same atomic # as original element
- isotopes
-
what is this an example of:
6 C 12, 6 C 13, 6 C 14 - isotopes( same atomic #)(protons)
- these decay and give off energy
- radioactive isotopes
- instrument that detects radiation (Becquerel)
- geiger counter
- images of radiation (curie)
- imaging
- what level is the radioactive isotope that has chemical properties like the stable isotopes?
- low level (radioactivity)
- what can you do with this low level radioactivity?
- substitute a small amount for the original element
- what is the small substitute amount called?
- a "tracer"
- When one uses a "tracer" what is it called?
- "labeling"
- WHat is an example of use of low level radiation?
- PETSCAN
- what does PETSCAN stand for?
- "position emission tomography"
- WHat does the PETSCAN use?
- labeled glucose
- What are the 4 negative points for high level radiation?
-
-they are carcinogens
-they damage DNA
-they are toxic
-they cause cancer - what are the positive uses of high level radiation?
-
-used to sterilize medical equipment
-zaps mail to detect anthrax
-radiation therapy for cancer patients
-injection of radiation(into prostate gland for cancer) - what charges attract?
- positive and negative charges
- what charges repel?
- like charges
- what do plants convert sunlight to?
- chemical energy
- what are 3 diatomic elements?
- O2, H2, N2
- this contains 2 or more atoms
- a molecule
- this must have 2 different elements?
- a compound
- what is present between chemical bonds of diff. elements?
- energy
- WHat are the 3 types of bonds?
- ionic, covalent, hydrogen
- this bond is held together by an attraction b/t positive an dnegative charged ions
- ionic bond
- ions are electrically charged
- ions are electrically charged
- NaCl<--->Na+Cl- is an example of what?
- dissociation
- this bond shares electrons, they can share either 1,2,or3 electrons
- covalent bonds
- name 2 types of covalent bonds
- polar and non-polar
- this covalent bond is an unequal sharing of electrons
- polar
- this covalent bond is an equal sharing of electrons
- non-polar
- attraction of an atom for electrons in a covalent bond
- electronegativity
- The greater the # of protons the ________ the electronegativity
- greater
- this bond is the weakest of the 3 types, it is what bonds water, it is between polar molecules "neighborhood bonding"
- hydrogen bond
- oxygen has the ________ charge
- negative
- the fact that oxygen is the negative charge is called
- electronegative
- hydrogen has the ____ charge
- positive
- the fact that hydrogen has a positive charge is called what?
- electropositive
- the greater the hydrogen bonds, the ____ the bond is
- stronger
- what is the function of the hydrogen bond?
- help maintain proper structure and function
- this is the universal component
- water
- water is a ___ molecule
- polar
- water makes up ______% of our bodies
- 70-90%
- frozen water is __ dense than liquid water
- less
- water has a ___ surface tension
- high
- what does it mean that water is cohesive?
- the molecules cling to each other, they are excelent transport mediums(inblood)
- what does it mean to say that water is adhesive?
- the molecules cling to polar surfaces
- what does hydrophylic mean?
- "loves water" dissociates easily in mixtures
- what does hydrophobic mean?
- "hates water", example is oil and water(don't mix)
- what does it meean to say that water has a high heat of vaporization?
- it takes 540 calories per gram to take hot water and change to gas
- water has a high heat capacity
- water has a high heat capacity
- the heat required to increase 1 gram of h2o by 1 degrees C
- calorie
- a kilocalorie, ,amt to increase 1kg (1L) of water
- CALORIE
- water has the ability to absorb more heat
- water has the ability to absorb more heat
- water doesn't freeze as quickly as others do
- water doesn't freeze as quickly as others do
- 1 gram from 1 degrees C, takes 80 calories to freeze
- our body temps change slowly
- The Ph Scale runs from ___to___
- 0-14
- a substance is an acid if it is___to___
- 0-6.99
- a substance is neutral if it is ___
- 7
- a substance is a base if it is ___to___
- 7.01-14
- the higher the concentration of ions, the ____ the # on the scale
- lower
- this acid is weak and serves as a buffer
- carbonic acid
- What is arterial blood on the PH Scale?
- 7.4
- during this the H+ are rising, bicarbonate HCO3(base) (changes strong acid to a weak buffer)
- acidosis
- during this OH + H2 O CO3--> HCO3 + -H2O ( buffers counteract strong acids and bases to maintain phisiological PH
- alkalosis
- how many electrons does carbon have in teh outer shell?
- 4
- organics are______
- living things
- in-organics are _______
- non-living things
- what are the skeletal backbones?
- carbon chains
- what attatches to carbon chains?
-
functional groups
H H H
C-C-C
H H H - what group is the one that is involved in chemical reactions?
- the functional group
- Write out each of the groups 3 times each on paper(figure 3.2) !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
- !!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
- what determines the type of reaction and dictates polarity of the molecule?
- functional groups
- molecules that have the same structures are called
- isomers
- these make up our cells(carbs,lipids,proteins,nucleic acids)
- macro molecules
- same type sub-units
- monomers
- largest macro molecules, made of monomers linked together
- polymers
- a condensation reaction to synthesis a type of macro molecule
- dehydration
- this is when water is used to break bonds that hold sub-units together
- hydrolysis
- these speed up chemical reactions by bringing reactants together
- enzymes
- sometimes, monomers must be__________________________
- activated before they react!
- what are the 2 main functions of carbohydrates?
- energy and structure
- what is a carb basic structure?
- CH2O
- what are the 3 hexoses (6 carbon rings)??
- glucose, fructose, galactose
- what is glucose?
- C6 H12 O6
- what reaction holds these rings together?
- dehydration
- these are simple sugars (b/t 3-7 carbons)
- monosaccharides
- what is a pentose?
-
a 5 carbon ring
(ribose, and deoxyrbose) - * name 3 isomers
- glucose, fructose, galactose
- this is energy produced in the cells(glycolysis)
- cellular respiration
- 2 sugars linked togethr
- disaccharides
- what are the 3 disaccharides?
-
maltose (glu.+glu)
Sucrose (glu.+fru)
lactose (glu.+gal) - plants main sugar
- sucrose
- humans main sugar
- glucose
- a bunch of sugars linked together
- polysaccharide
- plants store energy in the form of________
- starch
- humans store energy in the form of ________
- glycogen
- ideal blood sugar level is b/t ____ an ____
- 70-100
- what blood sugar level is acceptable?
- 110
- what blood sugar level is pre-diabetic?
- 111
- hormone that regulates blood sugar leval?
- insulin
- what holds the glycogen stored in our bodies?
- liver + skeletal muscle
- what reaction breaks down the glycogen?
- hydrolysis
- what is left over glycogen stored as?
- fat!
- what is the plants structural molecules?
- cellulose
- can animals break down cellulose?
- yes! they have micro-organisms that break it down!
- how do humans use cellulose?
- as roughage
- this is the structural carbohydrate exo-skeleton of crabs and lobsters
- chitin
- the micro organism that makes up the cel wall in bacteria
- peptidoglycon
- these are insoluable in water
- lipids
- these are made up of 1 glycerol and 3 fatty acids
- triglycerides
- how long can a long carbon chain be?
- 16-18 carbons long
- what are the electrons on the outer shells called?
- valance electrons
- what are the 2 types of fatty acids?
- saturated and un-saturated
- which fatty acid is solid at room temp?
- saturated
- saturated fats have a lot of hydrogen
- unsaturated fats have a little or no hydrogen
- which fatty acid is oil at room temp?
- un-saturated
- the build up of sat. fats in arteries
- Atherosclerosis
- which fats are found in the cell / plasma membrane
- phospholipids
- this has a hydrophylic head and a hydrophobic tail
- phospholipids
- this type of fat is made of cholesterol(4 carbon rings linked together)
- steroids
- what are the 2 steroid hormones?
- estrogen and testosterone
- Which is the bad choloesterol?
-
LDL
(low density) - which cholesterol is good to have more of?
-
HDL
(high density) - what are waxes?
- long chain fatty acids that binds to a long chain alcohol
- waxes are hydrophobic, solid at room temp, and have a high melting point
- waxes are hydrophobic, solid at room temp, and have a high melting point
- 50% of dry weight of cells consist of what?
- protein
- what are the building blocks of proteins?
- amino acids
- how many common amino acids are there in the cells?
- 20
- what are the 6 functions of amino acids?
-
support
enzymes
transport
hormones
defense
motion - 2 forms of protein that support:
-
keratin
collagen - speed up the rates of reactions:
- enzymes
- this carries to other parts of body, hemoglobin carries oxygen, channel, carriers int eh membranes
- transport
- these are regulatory "intercellular messangers"
- hormones
- antibodies are used in
- defense
- what 2 proteins put teh skeletal muscle into motion?
-
actin
myosin - 2 amino acids joined
- peptide
- more than 2 amino acids joined
- polypeptide
- what are the 4 levels of structure?
- primary, secondary, tertiary, quaternary
- what level of structure is the sequence of amino acids?
- primary
- what level of structure is shaped like a helix or beta pleated sheets (hydrogen bonds form)
- secondary
- what level of structure is the final 3d shape of actual protein molecule?
- tertiary
- what level of structure is bonding between R groups going on?
- Tertiary
- what are globular proteins?
- enzymes
- what are protein shape changes called?
- denaturation
- what level of structure is 2 or more ploypeptides joined together?
- quarternary
- this helps new protein fold into proper shape
- chaperone protein
- malfunctioning chaperone =
- diseases such as cystic fibrosis and alzheimer's
- misfolded proteins causing others to misfold as well (disease is formed)
- prion
- these are polymers of nucleotides
- nucleic acids
- this stores info regarding it's own replication + the order in which amino acids are to be joined to make protein
- DNA
- sugar = deoxyribose
- sugar = deoxyribose
-
p (phosphate)
\ /n-containing base
\S
|
H - nucleotide
- pyrimidines, purines, are what??
- nitrogen containing bases
- what are the 3 pyrimidines(single rings)?
-
cytosine
thymine
uracil - what are the 2 purines(double rings)??
-
adenine
guanine - this is a single strand polymer of nucleotides
- RNA
- What is the difference between DNA and RNA?
- RNA has uracil instead of DNA's thyamine
- what are the complimentary base pairs?
-
A-T G-C
adenine quanine
thyamine cytosine - what is "adenosine diphosphate"?
- ATP
- adenosine means what5?
- that adenine is bonded to ribose
- what happens with the diphosphate?
- gets rid of the last phosphate and becomes ADP, which becomes more stable and releases energy
- the ability to do work or bring about change
- energy
- 5 points under energy?
-
growth
development(maturation)
locomotion
metabolism
reproduction - what are the 4 type of energy?
- kinetic, potential, chemical, mechanical
- energy stored in food stuffs
- chemical
- moving a force through a distance
- mechanical energy
- energy of motion
- kinetic
- stored energy
- potential
- conservation-energy can't be created nor destroyed, only changed from one form to another
- 1st law of thermodynamics
- what is main source of 1st law?
- solar energy
- energy cannot be changed from one form to another without a loss of heat
- 2nd law of thermodynamics
- what must there be in order for energy to be changed from one form to another?
- loss of heat
- disorganization of particles(collisions) is called what
- entropy
- the sum of all chemical reactions that occur in a cell
- metabolism
- what energizes reactions that take place in the cell?
- ATP
- free energy is
- available energy
-
+G = gain in energy
-G = release of energy -
+G = gain in energy
-G = release of energy - this reaction goes from a higher energy level to a lower one
- exergonic
- this reaction goes from a lower level of energy to a higher one
- endergonic
- WHat is very versatile?
- ATP
- this reaction utilizes ATP, energy from teh ATP goes straightinto another reaction
- coupling reaction
- this atp energy synthesises macromolecules
- chemical
- this atp energy pumps molecules across membranes against concentration gradiants
- transport work
- this atp energy contacts the muscles
- mechanical
- these speed up the rate of the reactions
- enzymes
- what is another name for reactants?
- substrates
- this is the energy required to activate a chemical reaction
- energy of activation
- this is the portion of the enzyme that will attatch to substrates
- acive site
- this is when the enzyme undergoes alteration to acheive best fit
- induced fit model
- most enzymes just complex with their substrates, but what do some also do?
- participate in the actual reaction!
- what 2 things affect the rate of the reaction?
-
amount of substrate(reactants)
+
temperature - these are trace elements like (Cu)
- inorganic
- co-enzymes-these particular enzymes are non-protein(they are vitamins)
- organic
- it slows down the reaction when these things are lacking
- inorganic trace elements and organic co-enzymes
- oxidized is the ____ of electrons and H+
- loss
- reduced is the ____ of electrons an H+
- gain
- solar---> glucose + O2
- photosynthesis
- where does cellular respiration occur?
- in the mitochondria
- during cellular respiration what and what are turned into ATP?
- fat and glucose
- in the photosynthesis reaction, which is being reduced and oxidized?
- water is being oxidized because it is losing its electrons, and carbon dioxide is being reduced because it is gaining electrons
- this is involved in massive ATP production
- electron transport chain
- what is left after an ATP production is finished?
- free energy!!
- what is the term for producing atp from H+ ion gradient pumping back and forth across a membrane
- chemiosmosis
- an enzyme that facilitates production of ATP in a membrane
- ATP synthase
- what do chromosomes contain?
- genes that contain DNA
- what kind of replication is DNA?
- semi conservative from double helix to 2 single helixs
- steps to DNA replication
-
1-unwinding(unzip)
2-complementary base paring( A+T G+C)
3- joining - what is important to getting A to join T and G to join C?
- DNA polymerase
- these are bacteria that have quick replication
- prokaryotics
- this type divides by DNA bubbles spreading and it ends up with a pair of DNA strands
- Eukaryotic
- WHat 2 species are eukaryotic?
- humans and animals
- an error in matching up of base pairs
- genetic mutation
- what are some of the ways damage can be done to the DNA?
- toxins, nuclear spills, free radicals, tobacco smoke, pollutants, pesticides, uv rays
- what is the segment of the DNA strand that codes/specifies the amino acid sequence of a protein
- gene
- what do genes give the codes to?
- RNA
- what does RNA do with the codes?
- it delivers it into the cell
- what happens when the codes are inside of the cell thanks to RNA?
- "gene expression" occurs
- what is gene expression?
- "producing a protein"
- what are teh 3 types of RNA?
- mRNA, tRNA, rRNA
- this RNA delivers genetic messages(codes)
- mRNA (messanger)
- this RNA brings raw material to produce amino acids
- tRNA (transfer)
- this RNA is part of te ribosome where polypeptides are produced
- rRNA(ribosomal RNA)
- what are teh 2 steps to "gene expression"?
- transcription and translation
- this step is short, it occurs in the nucleus, it involves the mRNA
- transcription
- what are the 3 steps of translation?
- initiation, elongation, termination
- the step under translation that brings over teh amino acids, codons, and anticodons
- initiation